Sarcoidosis of the pleura-case repots

Abstract Introduction: Pleural involvement is an uncommon manifestation of sarcoidosis. It may manifest as a pleural effusion, pneumothorax, pleural thickening and nodules, hydropneumothorax, trapped lung, hemothorax, or chylothorax. The incidence of pleural effusion with sarcoidosis ranges from 0 to 5% but has been reported to be as high as 7.5%. Pleural effusions complicate sarcoidosis in <3% of patients. Case report: This is the case report of a 64 year old male patient with chronic multiorgan sarcoidosis. This patient developed pleural sarcoidosis with massive pleural effusion several years after the diagnosis of sarcoidosis.  A definitive diagnosis of a sarcoid pleural effusion was based on a biopsy demonstrating noncaseating granuloma. He responded well to treatment (Methotrexate plus Metilprednisolon) with complete withdrawal of the pleural effusion following five weeks of treatment. Conclusion: This is a rare case of pleural involvement of sarcoidosis with massive effusion. Key words : sarcoidosis, pleural effusion Apstrakt Uvod: Zahvacenost pleure je retka manifestacija sarkoidoze. Može se manifestovati kao pleuralni izliv, pneumotoraks, pleuralno zadebljanje I nodulima, hidropneumotoraks, zarobljena pluca, hemotoraks ili hilotoraks. Ucestalost pleuralnog izliva kod sarkoidoze se krece od 0 do 5% ali može biti I visa do 7,5%. Zahvacenost pleure kod sarkoidoze javlja se u <3% bolesnika. Prikaz bolesnika: Ovo je prikaz slucaja 64 godine starog bolesnika sa hronicnom multiorganskom sarkoidozom. Prikazan bolesnik razvija pleuralnu sarkoidozu  sa masivnim pleuralnim izlivom nekoliko godina nakon postavljanja dijagnoze sarkoidoze. Definitivna dijagnoza sarkoidoznog pleuralnog izliva postavljena je na osnovu biopsije koja je pokazala nekazeifikovani granulom. Bolesnik je dobro odregovao na terapiju (Methotrexate plus Metilprednisolon) sa kompletnim povlacenjem pleuralnog izliva posle pet nedelja lecenja. Zakljucak: Ovo je redak slucaj pleuralne zahvacenosti sarkoidozom sa masivnim pleuralnim izlivom. Kljucne reci : sarkoidoza, pleuralni izliv