High prevalence of elevated blood pressure among children with neurofibromatosis type 1

Background Neurofibromatosis type 1 (NF1) is a common neurocutaneous disease characterized by cafe-au-lait spots, axillary and inguinal freckling, neurofibromas, and optic gliomas. Increased rates of hypertension (HTN) were reported among NF1 patients, however, the prevalence of HTN and pre-HTN in pediatric NF1 patients has not been clarified.