[Effects of iron deficiency on toxic action of nitrites and endogenous synthesis of N-nitrosamines].

: Separate or joint ingestions of water solutions of sodium nitrite and/or N-diethylamine by rats fed iron deficiency diet caused sharp increasing of N-nitrosodiethylamine level in stomach, a decreasing of Hb and increasing of MetHb concentrations in blood of animal. These effects were greater on iron deficient diet than on control diet. The nitrite ingestion caused a decline level of cytochrome P-450 and inhibition of lipid peroxidation in rat liver.