194-LB: Effectiveness of Following Mediterranean Diet (MedDiet) Recommendations in the Real World in the Incidence of Gestational Diabetes Mellitus (GDM) and Adverse Maternal-Fetal Outcomes: A Prospective, Universal Interventional Study

Background: We previously reported that a MedDiet, supplemented with extra-virgin olive oil (EVOO) and pistachios, reduces GDM incidence (WHO criteria) and several adverse outcomes. To assess effects in the in the real world we evaluated the adoption of a MedDiet starting at the 1st gestational visit on the rate of GDM (compared with the control group/CG and intervention group/IG from the previous trial). We also compared the rate of adverse perinatal outcomes between women with and without GDM. Research Design and Methods: This is a prospective, clinic-based, interventional study with a single group. All normoglycemic women attending their 1st gestational visit Results: GDM rate was of 13.9%; this was significantly lower than the CG: RR 0.81 (0.73-9.28),p Conclusion: This study translates evidence to clinical practice, providing a universal and easy-to-apply approach to reduce GDM. An early nutritional intervention before GDM diagnosis ameliorates differences in maternofoetal adverse outcomes between GDM and no-GDM women. Disclosure A. Duran: None. N. Garcia de la Torre: None. C. Assaf-Balut: None. L. Del Valle: None. J. Ines: None. J. Valerio Deogracia: None. E. Bordiu: None. M. Fuentes: None. A. Barabash: None. M. Cuesta: None. M.A. Rubio: None. A.L. Calle: None. Funding Instituto de Salud Carlos III of Spain; Fondo Europeo de Desarrollo Regional; Sociedad de Endocrinolog?a Nutrici?n y Diabetes de la Comunidad de Madrid (IPI/2017/NR2)