Naringin alleviates H2O2-induced apoptosis via the PI3K/Akt pathway in rat nucleus pulposus-derived mesenchymal stem cells

Liping Nan,Feng Wang,Di Ran,Shifeng Zhou,Yang Liu,Zhen Zhang,Zenan Huang,Ze-Yu Wang,Jingcheng Wang,Xinmin Feng,Liang Zhang

Naringin alleviates H2O2-induced apoptosis via the PI3K/Akt pathway in rat nucleus pulposus-derived mesenchymal stem cells

2019

Liping Nan
Feng Wang
Di Ran
Shifeng Zhou
Yang Liu
Zhen Zhang
Zenan Huang
Ze-Yu Wang
Jingcheng Wang
Xinmin Feng
Liang Zhang

ABSTRACTPurpose: To investigate the protective effect of naringin (Nar) on H2O2-induced apoptosis of nucleus pulposus-derived mesenchymal stem cells (NPMSC) and the potential mechanism in this proc...

Keywords:

PI3K/AKT/mTOR pathway
Biochemistry
Apoptosis
Cell biology
Mesenchymal stem cell
Biology
Nucleus
Naringin
Oxidative stress
Viability assay
Annexin
TUNEL assay
Reactive oxygen species
Mitochondrial ROS
Molecular biology

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