The Role of Liver and Kidney on the Pharmacokinetics of a Recombinant Amino Terminal Fragment of Bactericidal/Permeability-Increasing Protein in Rats

Robert J. Bauer,Kenneth Der,Nneka Ottah-Ihejeto,Jennifer Barrientos,Ada H. C. Kung

The Role of Liver and Kidney on the Pharmacokinetics of a Recombinant Amino Terminal Fragment of Bactericidal/Permeability-Increasing Protein in Rats

1997

Robert J. Bauer
Kenneth Der
Nneka Ottah-Ihejeto
Jennifer Barrientos
Ada H. C. Kung

Purpose. The pharmacokinetics of rBPI23, a recombinant amino terminal fragment of bactericidal/permeability-increasing protein that binds to and neutralizes endotoxin, was investigated.

Keywords:

Heparin
Glycosaminoglycan
Drug interaction
Biochemistry
Bactericidal/permeability-increasing protein
Chemistry
Recombinant DNA
Pharmacokinetics
Kidney
Permeability (electromagnetism)

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