Transpulmonary lithium dilution technique: time to recalibration and calibration drift

We have previously demonstrated that an average of at least two curves is necessary to improve the calibration of the lithium dilution technique of the LiDCO™plus. The precision of the new calibration process is able to detect a least significant change (LSC) of 17% [1]. The primary aim of this study was to evaluate the drift after an initial calibration with two lithium dilution curves. The second aim of the study was to evaluate the relationship between the magnitude of the time to recalibration and the magnitude of the drift.