And improvements in relation to angiotensin II antagonists.

This invention provides FENIL and heterocyclic derivatives of the formula: OA pharmaceutically acceptable salt or solvated away. EACH A SUB 1, SUB 2 AND SUB A 3 is independently CH NO; X is -CO-, -CONH-, -NHCO-, -CONH- CH SUB 2, -O-, -NH-, -CH 2 SUB-SUB each R 1 is independently (CH SUB 2) SUB SUB NR 3; R SUB SUB 2 EN C 4 ADA R SUB 3 is independently -OH, -COOH, tetrazolyl-O 5; Each n is independently 0, 1, 2, 3, or 4; R SUB 4 is H, OH, halo, nitro, METHYL, AMINO, acetamido, methanesulfonamido O; Q is a bond or -O-; W is H, methyl, ethyl, O Hydroxy. Their pharmaceutical formulations and their uses RECEIVERS ANTOGONISTAS angiotensin II in mammals.