Adrenal Vein Sampling in Primary Aldosteronism: Sensitivity and Specificity of Basal Adrenal Vein to Peripheral Vein Cortisol and Aldosterone Ratios to Confirm Catheterization of the Adrenal Vein

Of the three cutoff values for basal adrenal vein to peripheral vein cortisol ratios reported in the literature (ie, ≥1.1, ≥2, and ≥3), the cutoff value of at least 2 offers the best sensitivity for 100% specificity, and sensitivity is improved with no decreased specificity by combining adrenal vein to peripheral vein aldosterone and cortisol ratios.