The Effects of Polysulfated Glycosaminoglycan (Adeqtiail®)on Activated Partial Thromboplastin Time, Prothrombin Time, Complete Blood Count, Biochemical Profile and Urinalysis in Cats

Polysulfated glycosaminoglycan (Adequan®) is a heparin analogue with chondroprotective and anticoagulant properties. A single intramuscular injection of 5 mg/kg and 25 mg/kg of polysulfated glycosaminoglycan in six healthy adult cats resulted in a transient, dose-de-pendent increase of activated partial thromboplastin time and prothrombin time. Minor changes were seen on complete blood count, biochemical profile and urinalysis.