Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

Jan Marquard,Silke Otter,Alena Welters,Alin Stirban,Annelie Fischer,Jan Eglinger,Diran Herebian,Olaf Kletke,Maša Skelin Klemen,Andraž Stožer,Stephan Wnendt,Lorenzo Piemonti,Martin Köhler,Jorge Ferrer,Bernard Thorens,Freimut Schliess,Marjan Rupnik,Tim Heise,Per-Olof Berggren,Nikolaj Klöcker,Thomas Meissner,Ertan Mayatepek,Daniel Eberhard,Martin Kragl,Eckhard Lammert

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

2015

NMDA receptors in pancreatic beta cells inhibit glucose-stimulated insulin secretion, and inhibiting these receptors with an over-the-counter medication improves diabetes in mouse models

Keywords:

Insulin
Pancreatic beta Cells
Drug
Immunology
Secretion
NMDA receptor
Diabetes mellitus
Medicine
Receptor
Endocrinology
Internal medicine
insulin secretion
diabetes treatment

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