Cholestanol co crystal of vitamin D3 and its preparation method and application

The invention belongs to the technical field of medicinal chemistry and crystallization process, and discloses cholestanol co crystal of vitamin D3 and its preparation method. By means of X-ray powder diffraction analysis, thermogravimetric analysis, differential scanning calorimetry and other means, the co crystal is comprehensively characterized to find that the co crystal has more excellent physical chemical and pharmaceutical properties. The preparation method of the co crystal of the vitamin D3 is simple, easy to control and good in reproducibility, and the target co crystal can be stably obtained.