Abstract 15615: Value of Mitral Annular Displacement by Speckle-tracking Echocardiography for Assessment of Left Ventricular Longitudinal Systolic Dysfunction in Patients With Severe Aortic Stenosis and Preserved Ejection Fraction

Background: Previous studies have reported that left ventricular (LV) global longitudinal strain (GLS) can be used for detection of LV longitudinal dysfunction in patients with severe aortic stenosis (AS) and preserved ejection fraction (EF). Application of speckle-tracking echocardiography to the mitral annuls provides rapid assessment of mitral annular displacement (MAD). This simple method may be used as a new index for longitudinal dysfunction in patients with AS. Thus, we examined the value of MAD by speckle-tracking echocardiography for the assessment of LV longitudinal systolic dysfunction in patients with severe AS and preserved EF. Methods: We studied 50 patients with severe AS (aortic valve area ≤ 1.0 cm 2 ) and preserved EF (≥ 50%) in whom GLS was successfully obtained by speckle-tracking echocardiography (QLAB 10, Philips Medical Systems). MAD was automatically and quickly assessed with QLAB 10 as the base-to-apex displacement of mid-point of both septal and lateral annuls in 4-chamber view. The percentage of MAD to LV length from the mid-point of mitral annuls to the apex at end-diastole (% mid-MAD) was calculated (Figure). The study population was divided into two groups; 15 patients with decreased longitudinal systolic function (GLS > -16%; Group-A) and 35 patients with preserved longitudinal systolic function (GLS ≤ -16%; Group-B). Results: Both GLS and MAD were successfully assessed in 49 of 50 patients (98%). A good correlation was shown between GLS and % mid-MAD in the study patients (r=-0.80, p Conclusions: MAD which is rapidly estimated by speckle-tracking echocardiography is useful in the assessment of LV longitudinal systolic dysfunction in patients with severe AS and preserved EF.