Proteomic Analysis Reveals Novel Protein Targets of S-Nitrosylation in Mesangial Cells

An apparatus and a method for the preforming and rounding of a book block. A support strip is arranged at an adjustable loading height for accommodating a fore-edge of the book block to be rounded. A transport device transports the book block at the loading height toward the support strip. A preform press is adjustable in a vertical direction above the back of the book block and includes at least two preforming tools. A rounding device including two rounding rolls driven in opposite directions for rotation around parallel rotational axes clamps the book block between the two rounding rolls for rounding the book block. At least a first drive is connected to at least one of the preforming tools to displace at least one of the preforming tools in a longitudinal direction extending parallel to the rotational axes to change a spacing between the preforming tools in the longitudinal direction.