Benzilic Acid Rearrangement Type Reaction of Physalins to Neophysalins. Structural Revision of One of the Dehydration Products of Physalin A.

Abstract The previously proposed structure of an acid-induced dehydration product of physalin A, a 13,14-seco-16,24-cyclosteroid, is revised as having a new carbon skeletal structure named neophysalin. The reaction from physalins to neophysalins proceed via a kind of the benzilic acid rearrangement.