Selective conversion of an enantioenriched cyclononadienone to the xeniolide, xenibellol, and florlide cores: an integrated routing strategy
2011
Members of the xenicane superfamily induce a variety of biological responses in vitro. In order to enable a better understanding of the function of these substances, we have developed a strategy that integrates the synthetic routes to many of its members. The core ring systems of the xeniolide, xenibellol, and florlide natural products were constructed stereoselectively from an enantioenriched cyclononadienone. The use of the cyclononadiene scaffold, reagent-controlled transannulations, and the parallels of these transformations to possible biosynthetic pathways of the natural product classes are discussed.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
76
References
12
Citations
NaN
KQI