N2-(2-methoxyphenyl)pyrimidine derivative, method for preparing same, and pharmaceutical composition for cancer prevention or treatment containing same as active ingredient

2016 
The present invention relates to an N2-(2-methoxyphenyl)pyrimidine derivative, a method for preparing the same, and a pharmaceutical composition for cancer prevention or treatment containing the same as an active ingredient. The N2-(2-methoxyphenyl)pyrimidine derivative according to the present invention, an optical isomer thereof, or a pharmaceutically acceptable salt thereof has excellent activity to inhibit anaplastic lymphoma kinase (ALK), thus has an excellent treatment effect on cancer cells having anaplastic lymphoma kinase (ALK) fusion proteins, such as EML4-ALK and NPM-ALK, and thus can be favorably used as a pharmaceutical composition for cancer prevention or treatment.
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