EVIDENCE OF IN VIVO TRANSFER OF A PLASMID ENCODING THE EXTENDED-SPECTRUM BETA-LACTAMASE TEM-24 AND OTHER RESISTANCE FACTORS AMONG DIFFERENT MEMBERS OF THE FAMILY ENTEROBACTERIACEAE

The epidemiological study of several multidrug-resistant Enterobacteriaceae isolated from five patients demonstrated in vivo dissemination of a 100-kb plasmid encoding the extended-spectrum β-lactamase TEM-24 from a clonal strain of Enterobacter aerogenes to different strains of Klebsiella pneumoniae, Escherichia coli, Proteus vulgaris, Proteus mirabilis, and Serratia marcescens.