A REVIEW ON NOVEL ORAL ANTICOAGULANTS

Plan: This article reveals the significance of novel oral anticoagulants in place of conventional vitamin K antagonists. Vitamin K antagonists were commonly used since 1941 but it has lot of inconveniences. Preface: Anticoagulants are drugs used to reduce the coagulability of blood. Mainly used for the prevention of disorders characterized by abnormal blood clots and emboli. Warfarin, a vitamin K antagonist was the only choice for chronic oral anticoagulation for more than half a century. It requires periodic monitoring of INR, its efficacy and safety depends upon time in the therapeutic range. Outcome: Recently novel oral anticoagulants (NOAC’s) have been introduced, offering similar effectiveness, safety and convenience of vitamin K antagonist not requiring lab monitoring. This review describes the currently approved NOAC’s.