Clinical analysis of hematologic changes on 25 Brucellosis patients

Objective To study the characteristics of hemogram and myelogram with Brucellosis patients.Methods 25 Brucellosis patients' bone marrow and peripheral blood smears were observed,at the same time a deep clinical inverstigation on the patients was conducted. Results The counts of blood cells were decreased in part pa-tients, and a typical lymphocytes were found in peripheral blood of 64% patients. The marrow proliferative activities were normal(92% ) or higher(8% ),and all patients had poisonous granules. Red cell proliferative activities were normal(68% ) or lower(32% ). The counts of megakaryocytes were normal,but the maturity of megakaryocyte was hindered. All patients' histocytes were increased at different degrees. NAP were increased. Conclusion The changes of hemogram and myelogram have clinical significance for diagnosis of Brucellosis, but primary hematologic disease with Brucellosis should be distinguished. Key words: Brucellosis; Leukocyte count; Bone marrow examination; Diagnosis,differential