Direct Rivaroxaban-Induced Factor Xa Inhibition Proves to be Cardioprotective in Rats

Sophie Guillou,Justine Beaumont,Sophie Tamareille,Sébastien Giraud,Delphine Mirebeau-Prunier,Fabrice Prunier,Laurent Macchi

Direct Rivaroxaban-Induced Factor Xa Inhibition Proves to be Cardioprotective in Rats

2019

Sophie Guillou
Justine Beaumont
Sophie Tamareille
Sébastien Giraud
Delphine Mirebeau-Prunier
Fabrice Prunier
Laurent Macchi

ABSTRACTBackground:Acute myocardial infarction is a leading cause of death worldwide. Though highly beneficial, reperfusion of myocardium is associated with reperfusion injury. While indirect inhibition of Factor Xa has been shown to attenuate myocardial ischemia-reperfusion (I/R) injury, the underl

Keywords:

Immunology
Myocardial infarction
Rivaroxaban
Cardiology
Diabetes mellitus
Cause of death
Internal medicine
Reperfusion injury
Medicine

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