Modified peptide vaccine from influenza m2

Matrix protein 2, one of the surface protein of influenza virus modified peptides and use method thereof (hereinafter, also referred to as "M2") derived is provided. The amino acid sequence of the influenza virus A type M2, peptides consisting of 2-24 th 23 amino acids (hereinafter, also referred to as "M2e") to a modified peptide insert a cysteine ​​residue, said alteration peptides and polypeptides fusion proteins, said alteration peptide or the influenza vaccine containing the fusion protein as an active ingredient, said influenza vaccine deliverable into the body containing devices, nucleic acid fragments comprising a nucleotide sequence encoding the amino acid sequence of said alteration peptide consisting of , expression vectors nucleic acid fragment is incorporated, a host expression vector has been introduced, and 該改 recognize varying peptide, an antibody having a protective effect against influenza viruses.