TCT-714 Transcatheter mitral valve replacement with balloon expandable valves in native mitral valve disease due to severe mitral annular calcification: Results from the first global registry

2015 
The risk of surgical mitral valve replacement in patients with severe mitral annular calcification (MAC) is very high due to comorbidities and technical challenges related to calcium burden, precluding surgery in many patients. There are few isolated reports of successful transcatheter mitral valve
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