원보 : 오리나무에서 분리된 Diarylheptanoid의 항산화작용 및 구조상관활성

Antioxidative activities againt 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical were evaluated for ten diarylheptanoids, 1,7-bis-(3,4-dihydroxyphenyl)-heptane-3-O-β-D-glucopyranosyl(1→3)-β-D-xylopyranoside(1), 1,7-bis-(3,4-dihydroxyphenyl)-heptane-3-O-β-D-apiofuranosyl(1→6)-β-D-glucopyranoside(2), 1,7-bis-(3,4-dihydroxyphenyl)-heptane-5-O-β-D-glucopyranoside(3), 1,7-bis-(3,4-dihydroxyphenyl)-5-hydroxyheptane(4), 1,7-bis-(3,4-dihydroxyphenyl)-heptane-3-one-5-O-β-D-glucopyranoside(5), oregonin(6), hirsutanonol(7), hirsutenone(8), 1,7-bis(3,4-dihydroxyphenyl)-5-hydroxyheptane-3-O-β-D-xylopyranoside(9) and platyphylloside(10), which were isolated from Alnus japonica. Aglycones(4,7 and 8) and mono glycosides(3,6 and 9) showed more strong antioxidative activities than diglycosides(1 and 2) against the DPPH radial. Especially, hirsutenone(8) showed superior activity among ten diarylheptanoid.