And combinations comprising antimuscarinic agents beta-adrenergic agonists

And combinations comprising antimuscarinic agents beta-adrenergic agonists. A combination comprising (a) a {2} be agonist and (b) an antagonist of M3 muscarinic receptors which is 3R- ( 2-hydroxy-2,2-dithien-2-ylacetoxy) -1- (3-phenoxypropyl) -1-azoniabicyclo [2.2.2] octane, in the form of a salt containing an anion X, which is a anion of a pharmaceutically acceptable acid mono or polyvalent.