Pathophysiology of Types of Pediatric and Adolescent Diabetes

In this chapter, we will describe the many and varied types of diabetes that can affect youth. We will also discuss the synthesis of insulin and mechanisms regulating β-cell secretion in non-diabetic individuals, as well as insulin-mediated glucose clearance. The development of hyperglycemia and pathogenesis of ketogenesis in type 1 diabetes will be presented, as well as differences between type 1 and type 2 diabetes.