Avaliação toxicológica da torta de pinhão-manso Jatropha curcas em ratos* Evaluation of toxicity bran Jatropha curcas

This study aimed to evaluate the effect of diets plus pie of Jatropha (Jatropha curcas l.) in performance and metabolism of male Wistar rats. 24 rats were used, albino males (Rattus norvegicus) in growth phase and initial average weight 109.38 ± 6, 16 g. The animals were weighed and randomly divided into two groups with 12 animals, constituting the treatments: control – standard diet and diets containing 4, 281TPM. Food consumption, body weight gain and feed conversion ratio of rats has been deprecated by the inclusion of Jatropha bran. The liver enzymes ALT and AST in rats fed diets increased Jatropha. The values of hemoglobin and hematocrit were within this range considered adequate for rodents. Not been reported differences in the electrolytic balance and respiratory metabolism. It is concluded that the inclusion of Jatropha pie in the feeding of rats depresses growth and development promotes hepatic deleterious changes.