Analysis of 24 cases of polycystic ovary syndrome after failed controlled ovarian hyperstimulation

ABSTRACT Some fertility patients with polycystic ovary syndrome (PCOS) undergoing controlled ovarian hyperstimulation (COH) experience ceased follicular growth during COH and fail to superovulate. In this article, 24 such PCOS patients resumed COH 15–20 days after previous COH treatment was stopped while patients were under ovarian downregulation. Seventeen cases achieved oocyte retrieval, of which 14 underwent embryo transfer and 12 resulted in clinical pregnancy. The remaining seven cases saw ceased follicular growth at 13 mm. This provides a rescue protocol for failed COH patients with PCOS.