Synapse maturation by activity-dependent ectodomain shedding of SIRPα.
2013
In this study, the authors document how SIRPα, a cell-adhesion molecule, participates in the late maturation of hippocampal excitatory synapses. They find that in response to activity, SIRPα sheds its ectodomain, which acts presynaptically to promote maturation in a process that requires CaM kinase, matrix metalloproteinases and the presynaptic receptor CD47.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
49
References
37
Citations
NaN
KQI