Minimum Alveolar Concentrations of Methoxyflurane, Halothane, Ether and Cyclopropane in Man: Correlation with Theories of Anesthesia

The minimum anesthetic concentration (MAC) required in man to prevent a muscular response to a skin incision in 50 per cent of the subjects was determined for cyclopropane, halothane, diethyl ether and methoxyflurane in man. These were (volumes per cent at one atmosphere pressure): cyclopropane 9.2,