Correlation between the detection rate of Multi-drug resistant Acinetobacter Baumannii and antimicrobial consumption

Objective To explore the correlation between the detection rate of multi- drug resistant Acinetobacterbaumannii and antimicrobial consumption. Methods Retrospective analysis was used to investigate the antibacterialconsumption in the Second Affiliated Hospital of Guangzhou Medical University from July 2011 to December 2013.Data ofdefined daily doses system of 100 bed per day(DDDs/100BD) as well as the results of multi- drug resistant Acinetobacterbaumannii detection in every six months was collected and their correlation was analyzed with Pearson statistic method bySPSS19.0 software. Results The consumption of carbopenems was positively correlated with detection rate of multi-drugresistant Acinetobacter baumannii(r =0.93, P0.05). There was no significant correlation in other drugs. Conclusion Toprevent rapid increase of multi-drug resistance rate, the antimicrobial consumption should be controlled and antibiotics shouldbe used rationally in accordance with clinical sensitivity test results as far as possible.