Tooth loss is independently associated with poor outcomes in stable coronary heart disease

ObjectiveWe investigated associations between self-reported tooth loss and cardiovascular outcomes in a global stable coronary heart disease cohort.MethodsWe examined 15,456 patients from 39 countries with stable coronary heart disease (prior myocardial infarction, prior revascularisation or multivessel coronary heart disease) in the STABILITY trial. At baseline, patients reported number of teeth (26–32 (all), 20–25, 15–19, 1–14 and no teeth) and were followed for 3.7 years. Cox regression models adjusted for cardiovascular risk factors and socioeconomic status, determined associations between tooth loss level (26–32 teeth: lowest level; no teeth: highest level) and cardiovascular outcomes.ResultsAfter adjustment, every increase in tooth loss level was associated with an increased risk of the primary outcome, the composite of cardiovascular death, non-fatal myocardial infarction and non-fatal stroke (hazard ratio 1.06; 95% confidence interval 1.02–1.10), cardiovascular death (1.17; 1.10–1.24), all-cause d...