Clinical effect of cervical plexus block thyroid operation with dexmedetomidine

Objective To observe the application effect of cervical plexus block thyroid operation with dexmedetomidine.Methods Selective thyroid operation in 60 cases,ASA Ⅰ or Ⅱ,were randomly divided into three groups:dexmedetomidine group (group D),midazolam group (group M) and control group (group C).The three groups were given improved method and the same application of cervical plexus block with local anesthetics.Dexmedetomidine of 1 μg/kg was infused before block in group D for 10 min,with constant speed,constant amount of 0.4-0.6 μg/(kg · h).In group M,intravenous injection of midazolam 0.04 mg/kg were given.The base value (T0),cervical plexus block after 10 min (T1),20 min (T2),30 min (T3) and SBP,DBP,HR,SpO2 and SBP and HR (RPP) at the end of openation (T4) were recorded.Results In group C,each indexes in T1-T4 were significantly higher than those in T0 (P ＜ 0.05) ; each indexes in group M and D T1-T4 were significantly lower than those in group C (P ＜ 0.05) ; each indixes in group D than in group M at T1-T4,but there was no significant difference (P ＞ 0.05).Conclusions Thyroid operation with dexmedetomidine sedation,analgesia effect is reliable,and can effectively inhibit the cardiovascular side effects in cervical plexus block. Key words: Dexmedetomidine ;  Cervical plexus block ;  Hemodynamics