Breast Cancer Risk May Increase After Childbirth. A Clinico-Epidemiological Study

Background: Several factors have been associated with the international variation in breast cancer incidence rates, these include epidemiologic, reproductive, hormonal and life style factors. Trends in these risk factors are important to demonstrate changes over time. Patients and Methods: This study was done to observe affected cases of early breast cancer according to age, parity, clinical signs and symptoms, site, side of breast lesion, pathology of malignant breast lump and type of surgery performed. The study includes Seven hundred and ninety (790) patients diagnosed with early breast cancer. Patient information already present in the data based archives at Damietta Cancer Institute, Damietta, and Mansoura University, Egypt, the period between January 2016 and December 2017. Results: Maximum number of early breast cancer was encountered in the 5th decade of age group of patients, followed by 4th decade. All cases studied were females except 9 cases which were males. The commonest sign and symptoms of presentation was painless lump in the breast followed by referred cases after surgery along with associated features of mastalgia, nipple discharge and axillary mass. Histopathologically, Infiltrating duct carcinoma represented most cases followed by medullary carcinoma & mucinous carcinoma. Conclusion: There are significant changes in reproductive and hormonal pattern in Egyptian females diagnosed with breast cancer over the period of our study.