A phase I study of novel multi-HLA-binding peptides and a new combination of immune adjuvants against solid tumors.

Hiroto Matsui,Shoichi Hazama,Koji Tamada,Keiko Udaka,Yasunari Koki,Toshinari Uematsu,Hideki Arima,Hiroyuki Furukawa,Tomoya Miyakawa,Shun Doi,Masahiro Kitahara,Shinsuke Kanekiyo,Yukio Tokumitsu,Yoshihiro Tokuhisa,Kazuhiko Sakamoto,Nobuaki Suzuki,Shigeru Takeda,Shigeru Yamamoto,Shigefumi Yoshino,Hiroaki Nagano

A phase I study of novel multi-HLA-binding peptides and a new combination of immune adjuvants against solid tumors.

2017

3086Background: Based on the exploratory analysis of our previous studies of peptide vaccine, we concluded that the combination of adjuvants hLAG-3Ig + Poly-ICLC is essential for controlling negati...

Keywords:

Pathology
Immunology
Immune system
Medicine
Human leukocyte antigen
exploratory analysis
Peptide vaccine
phase i study

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