Photosensitized Preparation of Fluorescent Luminarosine and Analogues

Abstract Optimized conditions for photosensitized preparation of green-yellow fluorescent (λEm = 530 nm) 7-β-D-ribofuranosylamino)pyrido[2,1 -h]pteridin-11-ium-5-olate (luminarosine) and its 2′-deoxy- and 2′-O-methyl- analogues, the key compounds in our studies on the synthesis of fluorescence-labeled oligonucleotides, have been developed. Article in memoriam of the late Professor Tsujiaki Hata