RESEARCH WORKS DONE ON RASASINDURA (SUBLIMATED MERCURIAL PREPARATION) - A CRITICAL REVIEW

Rasasindura (RS) sublimated mercurial preparation often used in diseases like Madhumeha (Diabetus mellitus), Rajayaksma (Tuberculosis), Pandu (Anaemia), Sthoulya (Obesity), Mandagni (Impaired digestive fire) etc. Mercurial preparations are constantly targeted due to lack of documentation and published works. Till date several research works have been carried out at institutional level on RS. Aim of the present work is to compile such research works done on RS in Department of Rasashastra and Bhaishajya Kalpana, Institute for Post Graduate Teaching and Research in Ayurveda, Jamnagar. Various pharmaceutical experiments revealed yield of RS ranging from 11.70% to 92.52% and was prepared in 6 hrs to 168 hrs. RS is HgS Hexagonal cinnabar with percentage of Mercury ranging from 82-85%. Safety of RS was established through acute and sub-chronic toxicity studies. Efficacy of RS was studied in diseases like Shukra kshaya (Infertility), Shwasa (Bronchial Asthma), Madhumeha (Diabetes mellitus), Kshudra kushta (Skin diseases), shwitra (leucoderma), Hypertention etc. In all the studies encouraging results were reported with decrease in signs and symptoms. Augmenting effect of RS was established by clinical studies.