A case of hemichorea associated with lung adenocarcinoma

An 81-year-old woman admitted to our hospital due to involuntary movement on her right extremities. Laboratory tests, including autoantibodies, were unremarkable and only age related changes were observed on brain MRI. Chest CT revealed lung adenocarcinoma. She was diagnosed as having paraneoplastic chorea. After removal of the tumor, her chorea was dramatically improved. One year after the operation, abnormal high intensity lesions were seen in bilateral caudate nuclei and globus pallidus on MRI. A part of the left caudate nucleus was enhanced by gadolinium. Here we show a clinical picture and neuroradiological findings of paraneoplastic chorea associated with lung adenocarcinoma.