Diagnosis and classification of axial spondyloarthritis : imaging and non-imaging features
2019
In this thesis the focus
was on diagnosing axSpA early using clinical features as well as imaging
modalities. We have studied multiple elements diagnosing axSpA among patients
presenting
with chronic back pain. We have emphasized two main themes: (1) the importance
of clinical
SpA features; and (2) the contribution of imaging to an axSpA diagnosis and
classification.
We have learned how rheumatologists use imaging results in their diagnostic
considerations
and thereby have helped reduce certain fears regarding the way diagnosis is
made in clinical
practice. We have shown that the use of MRI-spine in classification is not
efficient. The
common thread in all of the studies in this thesis is that axSpA diagnosis is
the interaction
between the clinical aspects of chronic back pain and imaging findings highly
suggestive of
axSpA. Clinicians should be aware of mindlessly ‘stacking up’ SpA features in
chronic back
pain patients in order to avoid unnecessary (biologic) treatment. Additional
studies are needed
to investigate the numerous phenotypes of axSpA and to predict in which chronic
back pain
patient axSpA diagnosis is likely.
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