Convenient synthesis of tetrahydroisoquinoline-hydantoins

Julie Charton,Sandrine Delarue,Sandrine Vendeville,Marie-Ange Debreu-Fontaine,Sophie Girault-Mizzi,Christian Sergheraert

Convenient synthesis of tetrahydroisoquinoline-hydantoins

2001

Julie Charton
Sandrine Delarue
Sandrine Vendeville
Marie-Ange Debreu-Fontaine
Sophie Girault-Mizzi
Christian Sergheraert

Abstract NaOH/MeOH or DIEA/CH 2 Cl 2 were convenient conditions for the synthesis in solution phase of hydantoins derived from Tic-OH and isocyanates.

Keywords:

Tetrahydroisoquinoline
Organic chemistry
Chemistry
solution phase
Combinatorial chemistry

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