Transgenic Mouse Technology in Skin Biology: Inducible Gene Knockout in Mice
2014
model systems are essential to investigate the contri-bution of the different proteins encoded by these genes to disease development. Furthermore, these models are neces-sary to develop and test new treatments for these diseases. Gene-targeting strategies in mice allow investigators to turn genes off or on, either in the whole organism or in a tissue-specific manner (Gu
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