CLINICAL OUTCOME OF THE FIRST TEN YEARS OF ULCERATIVE COLITIS AND PROCTITIS

Abstract 269 patients with ulcerative colitis and a history of less than 6 months when first seen at St. Mark's Hospital in the decade 1966-75 have been followed for up to 11 years. The outcome has been correlated with the maximum extent of the disease observed within 3 months of presentation. 75 patients required hospital admission, 56 within a year of presentation. Extensive colitis developed in 60 patients. The cumulative probability of the disease being extensive was 21% ±3% at 5 years and 29% ±4% at 10 years. 25 patients required surgical treatment. The cumulative probability of operation was 8% ±2% at 5 years and 15% ±4% at 10 years. 19 patients are known to have died. The expected number of deaths was 19·2.