Stereoselective Halocyclization of Alkenes With N‐Acyl Hemiaminal Nucleophiles

Halocyclization of alkenes was realized using N-acylhemiaminal nucleophiles. High diastereoselectivity could be achieved for the formation of three stereogenic centers in this halogen-mediated cyclization reaction. We also demonstrated that enantioselective bromocyclization of alkenes using N-acylhemiaminal nucleophiles was possible. Chirality 25:805–809, 2013. © 2013 Wiley Periodicals, Inc.