Small-Molecule Probes of Chromatin- Mediated Neuroplasticity: Histone Deacetylase Inhibitors as Memory Enhancers

A linear guide device is provided with a plurality of rolling elements. A guide rail extending in an axial direction thereof and including a plurality of rolling element rolling grooves in two side portions thereof is provided in the device, wherein the rolling grooves extend in an axial direction of the guide rail. A slider includes a plurality of rolling element rolling grooves respectively opposed to the rolling element rolling grooves of the guide rail, wherein the slider is supported on the guide rail in such a manner that the slider is movable along the axial direction of the guide rail through the rolling movements of the rolling elements respectively inserted between the rolling element rolling grooves of the slider. The slider includes a rolling element endless circulation track along which the rolling elements are allowed to circulate endlessly; and a plurality of separators, each interposed between the adjoining rolling elements in the circulation direction of the rolling elements. A clearance is formed between a line of the rolling elements and the separators which are endlessly circulated.