Kartagener's Syndrome and Intracytoplasm›c Injection of Ejaculated Immotile Spermatozoa Selected by Hypo-Osmot›c Swelling Test

Kartagener’s syndrome (KS) is a rare disorder which is defined as situs inversus accompanying defective cilial ultrastructure in ciliated cells and spermatozoa. Intracytoplasmic sperm injection is the treatment option for fathering a child in these cases. A few succesful pregnancies and healthy births have been reported in cases with KS treated with intracytoplasmic sperm injection using immotile spermatozoa. Here we present two cases of KS, succesfully treated by intracytoplasmic sperm injection combined with hypo-osmotic swelling test. In both cases, normal fertilization rates were achieved by using ejaculated immotile spermatozoa choosen by hypo-osmotic swelling test for the identification of the viable spermatozoa and in the first case, two cycles resulted in a healthy birth.