Potential Involvement of Type I Interferon Signaling in Immunotherapy in Seasonal Allergic Rhinitis
2016
Specific immunotherapy (SIT) reverses the symptoms of seasonal allergic rhinitis (SAR) in most patients. Recent studies report type I interferons shifting the balance between type I T helper cell (Th1) and type II T helper cells (Th2) towards Th2 dominance by inhibiting the differentiation of naive T cells into Th1 cells. As SIT is thought to cause a shift towards Th1 dominance, we hypothesized that SIT would alter interferon type I signaling. To test this, allergen and diluent challenged CD4
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
22
References
2
Citations
NaN
KQI