Dengue Envelope Domain III-Peptide Binding Analysis via Tryptophan Fluorescence Quenching Assay

Aida Baharuddin,a,b Asfarina Amir Hassan,a,c Rozana Othman,a,c,g Yongtao Xu,d Meilan Huang,d Bimo Ario Tejo,e Rohana Yusof,a,b Noorsaadah Abdul Rahman, f and Shatrah Othman*,a,b a Drug Design and Development Research Group, University of Malaya; b Department of Molecular Medicine, Faculty of Medicine, University of Malaya; c Department of Pharmacy, Faculty of Medicine, University of Malaya; f Department of Chemistry, Faculty of Science, University of Malaya; g Centre for Natural Product and Drug Discovery, University of Malaya; Kuala Lumpur 50603, Malaysia: d School of Chemistry and Chemical Engineering, Queen’s University Belfast; Northern Ireland BT7 1NN, United Kingdom: and e Center for Infectious Diseases Research, Surya University; Banten 15810, Indonesia. Received February 19, 2014; accepted July 12, 2014