Recent Developments in C–C Bond Formation Using Catalytic Reductive Coupling Strategies

Metal-catalyzed reductive coupling processes have emerged as a powerful methodology for the introduction of molecular complexity from simple starting materials. These methods allow for an orthogonal approach to that of redox-neutral strategies for the formation of C–C bonds by enabling cross-coupling of starting materials not applicable to redox-neutral chemistry. This short review summarizes the most recent developments in the area of metal-catalyzed reductive coupling utilizing catalyst turnover by a stoichiometric reductant that becomes incorporated in the final product. 1 Introduction 2 Ni Catalysis 3 Cu Catalysis 4 Ru, Rh, and Ir Catalysis 4.1 Alkenes 4.2 1,3-Dienes 4.3 Allenes 4.4 Alkynes 4.5 Enynes 5 Fe, Co, and Mn Catalysis 6 Conclusion and Outlook