CENTRAL GIANT CELL GRANULOMA IN THE PATIENT WITH EPIDERMAL NEVUS SYNDROME ASSOCIATED WITH HYPOPHOSPHATEMIC OSTEOMALACIA

Epidermal nevus syndrome has been used to describe the association of epidermal hamartomas and extracutaneous abnormalities, in this case including hypophosphatemic osteomalacia. The present case reports a female patient, 19 years of age, diagnosed with epidermal nevus syndrome and presenting with a central giant cell granuloma on the right side of the jaw, with facial asymmetry on the right side. The oral cavity revealed tooth displacement and bone expansion, and the patient reported pain during chewing. Alternative treatments or surgical resection were not well indicated in this case because of the systemic alteration, so treatment with partial resection of the central giant cell granuloma was proposed; this treatment reduced the lesion size and allowed for improved masticatory function. During the 9-month follow-up period, we observed better masticatory function, less facial asymmetry, and new bone formation in the jaw, thus considered a good result for the treatment performed.