The synthesis of 14С-etoxozepam ad determination of it`s main physico-chemical and radiochemical properties

The aim of this work was synthesis, identification and radiochemical characterization of 3-ethoxy-7-bromo-5phenyl-1,2-dihydro-3Н-1,4-benzodiazepine-2-one. The 14C-labeled compound (14С-etoxozepam) was synthesized from 7-bromo-5-phenyl-3-chloro-1,2-dihydro-3Н-1,4-benzodiazepine-2-one with 2[14С] – ethyl alcohol. The physics chemical constants (Тmelt., IR-, 1Н-NMR- and mass-spectra) are identical to the standard sample. The specific activity of the sample is 0,199 ± 0,001 Cu/mol (0,7 MBk/mol), and radiochromatographic purity – 96,2 %.